

Methods: Serum AFP, CEA, CA199 and SF levels were determined with chemiluminescence immunoassay (CLIA) in 49 patients with primary liver carcinoma, 7 patients with metastatic liver carcinoma, 40 patients with hepatic cirrhosis, 47 patients with HBV hepatitis and 30 controls. Objective: To investigate the diagnostic value of combined detection of four tumor markers in patients with possible malignant change in liver disorders. Therefore, it is suggested that AFP in pregnant women has substantial difference and regularity between different semesters but without any significant correlation with their agesĭiagnostic value of combined determination of serum AFP, CEA, CA199, SF levels in patients with primary hepatic carcinoma Later on it tends to decrease slowly, but still remains over 100 μg/l in parturition period. Then, it gradually increases from the 13th week and reaches its maximum (184.6 +- 74.6 μg/l) at 32nd week. The result shows that the AFP level is normal during the first 12 weeks of pregnancy.

All the data were made by statistical analysis. The authors have reported AFP level in the blood serum of 2223 normal pregnant women in different semesters by RIA method.

Wang Yunhui Huo Tongshu Ji Changqing Mei Nan Zhang Tao International Nuclear Information System (INIS) Study of AFP level in the blood serum of the 2223 normal pregnant women
